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proteome profiler mouse cytokine array  (R&D Systems)


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    R&D Systems proteome profiler mouse cytokine array
    Proteome Profiler Mouse Cytokine Array, supplied by R&D Systems, used in various techniques. Bioz Stars score: 98/100, based on 807 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/proteome profiler mouse cytokine array/product/R&D Systems
    Average 98 stars, based on 807 article reviews
    proteome profiler mouse cytokine array - by Bioz Stars, 2026-02
    98/100 stars

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    R&D Systems proteome profiler mouse cytokine array
    Proteome Profiler Mouse Cytokine Array, supplied by R&D Systems, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Galc and Lcn2 double KO brain has a dramatic reduction in microgliosis along with a significant downregulation of multiple pro-inflammatory cytokines. ( A ) Immunohistochemistry on brain cryosections and quantification show a significant decrease of CD68 level (green) in Galc −/− ; Lcn2 −/− compared to Galc −/− . ( B ) Whole brain RT-qPCR analysis of inflammatory cytokines shows a significant downregulation of the pro-inflammatory TNF-α, MMP-3, and MCP-1 transcripts in Galc −/− ; Lcn2 −/− versus Galc −/− . N = 3 for Galc +/+ and Lcn2 −/− . N = 5 for Galc −/− ; Lcn2 −/− and Galc −/− all with 2 technical replicates. Data are presented as mean values ± SEM; * P < 0.05 , ** P < 0.01 , *** P < 0.001 , and ns = not significant. ( C ) <t>Proteome</t> Profiler Mouse <t>Cytokine</t> Array, which can detect 111 different mouse cytokines simultaneously, shows that multiple cytokines such as CD40, CXCL5, CD93, and CX3CL1 are significantly downregulated in the Galc −/− ; Lcn2 −/− compared to Galc −/− at P40.
    Proteome Profiler Mouse Xl Cytokine Array Analysis, supplied by R&D Systems, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Galc and Lcn2 double KO brain has a dramatic reduction in microgliosis along with a significant downregulation of multiple pro-inflammatory cytokines. ( A ) Immunohistochemistry on brain cryosections and quantification show a significant decrease of CD68 level (green) in Galc −/− ; Lcn2 −/− compared to Galc −/− . ( B ) Whole brain RT-qPCR analysis of inflammatory cytokines shows a significant downregulation of the pro-inflammatory TNF-α, MMP-3, and MCP-1 transcripts in Galc −/− ; Lcn2 −/− versus Galc −/− . N = 3 for Galc +/+ and Lcn2 −/− . N = 5 for Galc −/− ; Lcn2 −/− and Galc −/− all with 2 technical replicates. Data are presented as mean values ± SEM; * P < 0.05 , ** P < 0.01 , *** P < 0.001 , and ns = not significant. ( C ) <t>Proteome</t> Profiler Mouse <t>Cytokine</t> Array, which can detect 111 different mouse cytokines simultaneously, shows that multiple cytokines such as CD40, CXCL5, CD93, and CX3CL1 are significantly downregulated in the Galc −/− ; Lcn2 −/− compared to Galc −/− at P40.
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    Galc and Lcn2 double KO brain has a dramatic reduction in microgliosis along with a significant downregulation of multiple pro-inflammatory cytokines. ( A ) Immunohistochemistry on brain cryosections and quantification show a significant decrease of CD68 level (green) in Galc −/− ; Lcn2 −/− compared to Galc −/− . ( B ) Whole brain RT-qPCR analysis of inflammatory cytokines shows a significant downregulation of the pro-inflammatory TNF-α, MMP-3, and MCP-1 transcripts in Galc −/− ; Lcn2 −/− versus Galc −/− . N = 3 for Galc +/+ and Lcn2 −/− . N = 5 for Galc −/− ; Lcn2 −/− and Galc −/− all with 2 technical replicates. Data are presented as mean values ± SEM; * P < 0.05 , ** P < 0.01 , *** P < 0.001 , and ns = not significant. ( C ) <t>Proteome</t> Profiler Mouse <t>Cytokine</t> Array, which can detect 111 different mouse cytokines simultaneously, shows that multiple cytokines such as CD40, CXCL5, CD93, and CX3CL1 are significantly downregulated in the Galc −/− ; Lcn2 −/− compared to Galc −/− at P40.
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    R&D Systems proteome profiler mouse xl cytokine array kit
    Galc and Lcn2 double KO brain has a dramatic reduction in microgliosis along with a significant downregulation of multiple pro-inflammatory cytokines. ( A ) Immunohistochemistry on brain cryosections and quantification show a significant decrease of CD68 level (green) in Galc −/− ; Lcn2 −/− compared to Galc −/− . ( B ) Whole brain RT-qPCR analysis of inflammatory cytokines shows a significant downregulation of the pro-inflammatory TNF-α, MMP-3, and MCP-1 transcripts in Galc −/− ; Lcn2 −/− versus Galc −/− . N = 3 for Galc +/+ and Lcn2 −/− . N = 5 for Galc −/− ; Lcn2 −/− and Galc −/− all with 2 technical replicates. Data are presented as mean values ± SEM; * P < 0.05 , ** P < 0.01 , *** P < 0.001 , and ns = not significant. ( C ) <t>Proteome</t> Profiler Mouse <t>Cytokine</t> Array, which can detect 111 different mouse cytokines simultaneously, shows that multiple cytokines such as CD40, CXCL5, CD93, and CX3CL1 are significantly downregulated in the Galc −/− ; Lcn2 −/− compared to Galc −/− at P40.
    Proteome Profiler Mouse Xl Cytokine Array Kit, supplied by R&D Systems, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/proteome profiler mouse xl cytokine array kit/product/R&D Systems
    Average 97 stars, based on 1 article reviews
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    R&D Systems proteome profiler mouse xl cytokine array kits
    Galc and Lcn2 double KO brain has a dramatic reduction in microgliosis along with a significant downregulation of multiple pro-inflammatory cytokines. ( A ) Immunohistochemistry on brain cryosections and quantification show a significant decrease of CD68 level (green) in Galc −/− ; Lcn2 −/− compared to Galc −/− . ( B ) Whole brain RT-qPCR analysis of inflammatory cytokines shows a significant downregulation of the pro-inflammatory TNF-α, MMP-3, and MCP-1 transcripts in Galc −/− ; Lcn2 −/− versus Galc −/− . N = 3 for Galc +/+ and Lcn2 −/− . N = 5 for Galc −/− ; Lcn2 −/− and Galc −/− all with 2 technical replicates. Data are presented as mean values ± SEM; * P < 0.05 , ** P < 0.01 , *** P < 0.001 , and ns = not significant. ( C ) <t>Proteome</t> Profiler Mouse <t>Cytokine</t> Array, which can detect 111 different mouse cytokines simultaneously, shows that multiple cytokines such as CD40, CXCL5, CD93, and CX3CL1 are significantly downregulated in the Galc −/− ; Lcn2 −/− compared to Galc −/− at P40.
    Proteome Profiler Mouse Xl Cytokine Array Kits, supplied by R&D Systems, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Galc and Lcn2 double KO brain has a dramatic reduction in microgliosis along with a significant downregulation of multiple pro-inflammatory cytokines. ( A ) Immunohistochemistry on brain cryosections and quantification show a significant decrease of CD68 level (green) in Galc −/− ; Lcn2 −/− compared to Galc −/− . ( B ) Whole brain RT-qPCR analysis of inflammatory cytokines shows a significant downregulation of the pro-inflammatory TNF-α, MMP-3, and MCP-1 transcripts in Galc −/− ; Lcn2 −/− versus Galc −/− . N = 3 for Galc +/+ and Lcn2 −/− . N = 5 for Galc −/− ; Lcn2 −/− and Galc −/− all with 2 technical replicates. Data are presented as mean values ± SEM; * P < 0.05 , ** P < 0.01 , *** P < 0.001 , and ns = not significant. ( C ) <t>Proteome</t> Profiler Mouse <t>Cytokine</t> Array, which can detect 111 different mouse cytokines simultaneously, shows that multiple cytokines such as CD40, CXCL5, CD93, and CX3CL1 are significantly downregulated in the Galc −/− ; Lcn2 −/− compared to Galc −/− at P40.
    Proteome Profiler Mouse Xl Cytokine Array Kit Purchased R D Systems, supplied by R&D Systems, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Galc and Lcn2 double KO brain has a dramatic reduction in microgliosis along with a significant downregulation of multiple pro-inflammatory cytokines. ( A ) Immunohistochemistry on brain cryosections and quantification show a significant decrease of CD68 level (green) in Galc −/− ; Lcn2 −/− compared to Galc −/− . ( B ) Whole brain RT-qPCR analysis of inflammatory cytokines shows a significant downregulation of the pro-inflammatory TNF-α, MMP-3, and MCP-1 transcripts in Galc −/− ; Lcn2 −/− versus Galc −/− . N = 3 for Galc +/+ and Lcn2 −/− . N = 5 for Galc −/− ; Lcn2 −/− and Galc −/− all with 2 technical replicates. Data are presented as mean values ± SEM; * P < 0.05 , ** P < 0.01 , *** P < 0.001 , and ns = not significant. ( C ) <t>Proteome</t> Profiler Mouse <t>Cytokine</t> Array, which can detect 111 different mouse cytokines simultaneously, shows that multiple cytokines such as CD40, CXCL5, CD93, and CX3CL1 are significantly downregulated in the Galc −/− ; Lcn2 −/− compared to Galc −/− at P40.
    Mouse Xl Cytokine Array Kit R D Systems Ary028 E Z N A, supplied by R&D Systems, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    R&D Systems mouse xl cytokine array kit
    Galc and Lcn2 double KO brain has a dramatic reduction in microgliosis along with a significant downregulation of multiple pro-inflammatory cytokines. ( A ) Immunohistochemistry on brain cryosections and quantification show a significant decrease of CD68 level (green) in Galc −/− ; Lcn2 −/− compared to Galc −/− . ( B ) Whole brain RT-qPCR analysis of inflammatory cytokines shows a significant downregulation of the pro-inflammatory TNF-α, MMP-3, and MCP-1 transcripts in Galc −/− ; Lcn2 −/− versus Galc −/− . N = 3 for Galc +/+ and Lcn2 −/− . N = 5 for Galc −/− ; Lcn2 −/− and Galc −/− all with 2 technical replicates. Data are presented as mean values ± SEM; * P < 0.05 , ** P < 0.01 , *** P < 0.001 , and ns = not significant. ( C ) <t>Proteome</t> Profiler Mouse <t>Cytokine</t> Array, which can detect 111 different mouse cytokines simultaneously, shows that multiple cytokines such as CD40, CXCL5, CD93, and CX3CL1 are significantly downregulated in the Galc −/− ; Lcn2 −/− compared to Galc −/− at P40.
    Mouse Xl Cytokine Array Kit, supplied by R&D Systems, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Galc and Lcn2 double KO brain has a dramatic reduction in microgliosis along with a significant downregulation of multiple pro-inflammatory cytokines. ( A ) Immunohistochemistry on brain cryosections and quantification show a significant decrease of CD68 level (green) in Galc −/− ; Lcn2 −/− compared to Galc −/− . ( B ) Whole brain RT-qPCR analysis of inflammatory cytokines shows a significant downregulation of the pro-inflammatory TNF-α, MMP-3, and MCP-1 transcripts in Galc −/− ; Lcn2 −/− versus Galc −/− . N = 3 for Galc +/+ and Lcn2 −/− . N = 5 for Galc −/− ; Lcn2 −/− and Galc −/− all with 2 technical replicates. Data are presented as mean values ± SEM; * P < 0.05 , ** P < 0.01 , *** P < 0.001 , and ns = not significant. ( C ) Proteome Profiler Mouse Cytokine Array, which can detect 111 different mouse cytokines simultaneously, shows that multiple cytokines such as CD40, CXCL5, CD93, and CX3CL1 are significantly downregulated in the Galc −/− ; Lcn2 −/− compared to Galc −/− at P40.

    Journal: Scientific Reports

    Article Title: Ablation of lipocalin-2 reduces neuroinflammation in a mouse model of Krabbe disease

    doi: 10.1038/s41598-024-82927-1

    Figure Lengend Snippet: Galc and Lcn2 double KO brain has a dramatic reduction in microgliosis along with a significant downregulation of multiple pro-inflammatory cytokines. ( A ) Immunohistochemistry on brain cryosections and quantification show a significant decrease of CD68 level (green) in Galc −/− ; Lcn2 −/− compared to Galc −/− . ( B ) Whole brain RT-qPCR analysis of inflammatory cytokines shows a significant downregulation of the pro-inflammatory TNF-α, MMP-3, and MCP-1 transcripts in Galc −/− ; Lcn2 −/− versus Galc −/− . N = 3 for Galc +/+ and Lcn2 −/− . N = 5 for Galc −/− ; Lcn2 −/− and Galc −/− all with 2 technical replicates. Data are presented as mean values ± SEM; * P < 0.05 , ** P < 0.01 , *** P < 0.001 , and ns = not significant. ( C ) Proteome Profiler Mouse Cytokine Array, which can detect 111 different mouse cytokines simultaneously, shows that multiple cytokines such as CD40, CXCL5, CD93, and CX3CL1 are significantly downregulated in the Galc −/− ; Lcn2 −/− compared to Galc −/− at P40.

    Article Snippet: The Proteome Profiler Mouse XL Cytokine Array analysis (R&D Systems #ARY028) was performed on whole brain lysates as previously described .

    Techniques: Immunohistochemistry, Quantitative RT-PCR